Favourite GAME: Yellow. It was my first game, and remains the most difficult to me thanks to the large gap in levels between Erika, and whoever you chose to battle out of Koga or Sabrina. Never figured out the best way to do that part of the game.
Favourite REGION: The Hoenn region. That of course could change with Black and White as I have not seen Unova. Looking forward to it!
Favourite CITY/TOWN: Sunyshore City. I loved the layout and it was my favourite music for any city.
Favourite EXPLORABLE DUNGEON: All versions of Victory Road. I love the challenges they bring.
Favourite LANDMARK ICON: Either Sprout Tower in Violet City, or Mt. Coronet.
Favourite ROUTE: Gosh this is a hard one. I'll pick one from each region.
Kanto - Not an individual one, but the routes from Lavender Town to Fuschia City
Johto - Route 44
Hoenn - Route 120
Sinnoh - Route 222 or 227
Unova - Don't know yet. Haven't played.
Favourite ALTERNATE WEATHER LOCATION: Route 216/217/Snowpoint City