I thought Yellow was the anime game? As far as another game being on the anime, the anime is a advertisement for a game series already. If that game series ends then bye bye Pokemon anime. What would you make anime Pokemon game about? Certainly not another RPG as it would just be a dumbed down version of the regular games only you'll be force to play as Ash through every region. Just the thought makes me shudder. They could make a new puzzle game with anime characters cameoing in it. That seems fine.
RIP anime version of Glovehead. Pokemon Adventures will save you.