I myself have tossed Serperior out and have put some other pokemon to good use, Instead of serperior being my lead starter, I now have DW Blaziken. This is my first time tossing a starter, and I also tossed my starter in Johto.
Personally I think Johto and Unova have the worst starters (other than cyndaquil and tepig).
Have you done anything like this?
*I say tossed as in out of your team!