Weezing is an interesting pokemon, only being weak to psychic, enabling an almost ideal partnership with Zoroark. As for a setup:
Simple enough set, poison them with Poison Gas or Toxic, and slam them with Venoshock. Flamethrower and Thunderbolt are for coverage, while Explosion can damage most things to the point of at least half health unless it is Steel/Rock type, in which case you shouldn't be fielding Weezing at all.
As for countering it, Psychic types are the way to go. one decent Psychic will floor it. Be wary of the fact that Zoroark may be shielding for it, due to the predictability of countering Weezings with Psychic type moves.
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Friend Safari- Phantump, Drifblim, Shuppet.
Time zone- London-GMT
Showdown alt: Delta-Omega
Started my journey into PASBL, let's see how I fare...